One of the most common concerns people express about their face as they age is the presence of smoker’s lines, or peri-oral rhytids, around the mouth. These stubborn lines are difficult to treat. It is important to seek not only a fellowship-trained but also a double board-certified facial plastic surgeon if you have aesthetic concerns about your face and/or neck.
Addressing Smoker’s Lines (Peri-Oral Rhytids)
Dr. Jeffrey Harmon
I Utilize a Dual-Pronged Approach: Resurfacing and Nano-Fat Transfer
Dr. Harmon often utilize a dual-pronged approach to treating peri-oral skin, including rhytids. The first prong involves the use of a refined form of an individual’s own fat, called nanofat. Nanofat is placed under the skin around the mouth. The second prong is a fractional CO2 laser, which is used after injecting nanofat. This laser resurfaces the skin which, along the with nanofat components, can encourage more organized collagen deposition, thereby improving the appearance of wrinkles and overall skin quality and texture (1, 2, 3, 4, 5, 6).
This approach can better address the actual changes going on in the skin – called histological changes – when compared with utilizing only one of the two prongs or hyaluronic acid filler to simply fill in the lines.

This 58-year-old patient came to Dr. Harmon to address sagging cheeks and jowls, loose tissue in her neck, facial wrinkles, and a lengthened upper lip. An extended deep plane facelift, neck lift, and lip lift were performed. Lip filler was added to balance out her bottom lip with her top lip. Finally, the patient underwent treatment with a fractional CO2 laser in addition to nano-fat grafting of the wrinkles around her mouth. The patient is thrilled with her results only a few months after surgery.
Trust Your Face to a Facial Plastic Surgeon
It is important to seek a double board-certified, fellowship-trained specialist in plastic surgery of the face and neck when you have concerns about your face or neck.
Why Choose Dr. Harmon
- The mission of Harmon Facial Plastic Surgery is to help people along their journey towards self-confidence, to feel good about feeling good.
- Dr. Harmon is a double board-certified facial plastic surgeon.
- Dr. Harmon values making patients feel welcomed, listened to, and respected.
- Dr. Harmon graduated with honors from Cornell University with a Bachelor of Science degree in molecular biology.
- Dr. Harmon earned his medical degree from the University of Cincinnati.
- Dr. Harmon underwent five years of extensive training in head at neck surgery at the prestigious residency program at the University of Cincinnati.
- Dr. Harmon then underwent focused fellowship training in cosmetic facial plastic surgery through the American Academy of Facial Plastic and Reconstructive Surgery (AAFPRS) with the world-renowned surgeon, Dr. Andrew Jacono, on Park Avenue in New York City.
Request a Consultation
Request a consultation with Dr. Harmon at Harmon Facial Plastic Surgery in Cincinnati. Visit our clinic. You will learn more about Dr. Harmon’s credentials, style and approach. Build a relationship with our dedicated team. Do not stop at searching “plastic surgery near me.” Get in touch with us today to learn more!
References
- Akbari F, Hadibarhaghtalab M, Parvar SY, Dehghani S, Namazi MR. Toward facial rejuvenation; A clinical trial to assess the efficacy of nano fat grafting on wrinkles. J Cosmet Dermatol. 2024 Feb;23(2):600-606.
- La Padula S, Ponzo M, Lombardi M, Iazzetta V, Errico C, Polverino G, Russo F, D'Andrea L, Hersant B, Meningaud JP, Salzano G, Pensato R. Nanofat in Plastic Reconstructive, Regenerative, and Aesthetic Surgery: A Review of Advancements in Face-Focused Applications. J Clin Med. 2023 Jun 28;12(13):4351.
- Tonnard P, Verpaele A, Carvas M. Fat Grafting for Facial Rejuvenation with Nanofat Grafts. Clin Plast Surg. 2020 Jan;47(1):53-62.
- Tonnard P, Verpaele A, Peeters G, Hamdi M, Cornelissen M, Declercq H. Nanofat grafting: basic research and clinical applications. Plast Reconstr Surg. 2013 Oct;132(4):1017-1026.
- Tran VVT, Jin X, Hong KY, Chang H. Effects of Nanofat in Plastic and Reconstructive Surgery: A Systematic Review. Plast Reconstr Surg. 2024 Sep 1;154(3):451e-464e.
- Uyulmaz S, Sanchez Macedo N, Rezaeian F, Giovanoli P, Lindenblatt N. Nanofat Grafting for Scar Treatment and Skin Quality Improvement. Aesthet Surg J. 2018 Mar 14;38(4):421-428.
This blog post is for educational purposes only and does not constitute direct medical advice. It is essential that you have a consultation with a qualified medical provider prior to considering any treatment. This will allow you the opportunity to discuss any potential benefits, risks, and alternatives to the treatment.